Secondary Metabolite Compounds and Secretory Structures of Medicinal Plants in the Piperaceae Family
DOI:
https://doi.org/10.35334/xrv5j894Keywords:
Secondary Metabolite, Piperaceae, Secretory Structures, Medicinal plants.Abstract
Species in the Piperaceae family have various benefits and can be used as medicines to treat different kinds of diseases. The metabolite secondary compounds in medicinal plants forms the basis of their medicinal properties, which have been utilized by various ethnics in Indonesia, such as the Dayak Kenyah tribe. This tribe uses plants from the Piperaceae family as traditional medicine. The use of these plants as medicine makes it necessary to analyze the secondary metabolite compounds and the location of their accumulation within the secretory structures using histochemical methods. Plant identification was carried out through direct interviews with local informants and verification at the Herbarium, Indonesian Institute of Sciences. Based on the research results, the plant organs used were mainly leaves, which are generally used as remedies for fever. The secretory structures found include idioblast cells and glandular trichomes, which commonly contain alkaloid and terpenoid compounds. The results of this study strengthen the evidence for the medicinal potential of the four Piperaceae species: Piper betle, Piper porphyrophyllum, Piper officinarum, and Piper ungaramense and indicate that they can be further developed through secretory cell culture techniques.
References
Aisyiyah, N.M., Siregar, K.A.A., Kustiawan, P.M. (2021). Review: Potensi daun Sirih merah (Piper crocatum) sebagai antiinflamasi pada Rheumatoid Arthritis. Jurnal Farmasi Sains dan Praktis (JFSP).7 (2): 197-206.
Amelia, D.P., Yusfarani, D. (2023). Pemanfaatan daun Sirih hijau (Piper betle L) di desa marga bakti kecamatan Sinar Peninjauan Kabupaten Ogan Komerin Ulu. Prosiding SEMNAS BIO 2023 UIN Raden Fatah Palembang ISSN : 2809-8447
Biswas, A., Ghorai , M., Mishra, T., et al. (2022). Piper longum L.: A comprehensive review on traditional uses, phytochemistry, pharmacology, and health-promoting activities. Phytother Res. 36(12):4425-4476. DOI: 10.1002/ptr.7649.
Bosabalidis AM. 2014. Idioblastic mucilage cells in Teucrium polium leaf. anatomy and histochemistry. Mod Phytomorphol. 5:49–52.
Esti Munawaroh, Inggit Puji Astuti, dan Sumanto. (2011). Studi keanekaragaman dan potensi suku Piperaceae di Sumatera Barat. Berk. Penel. Hayati Edisi Khusus: 5A (35–40).
Guo, J., Zhou, C. (2019). Secretory Structures of Pogostemon auricularius: Morphology, Development, and Histochemistry. Symmetry, 11(1), 13; DOI: 10.3390/sym11010013.
Harborne, B., “Metode Fitokimia Penuntun Cara Modern Menganalisis tumbuhan. Padmawinata K, Soediro I, Penerjemah; Niksolihin S, editor”, Penerbit Institut Teknologi Bandung, Ed ke-2, 1987.
Huang SS, Kirchoff BK, Liao JP. 2008. The capitate and peltate glandular trichomes of Lavandula pinnata L. (Lamiaceae): Histochemistry, ultrastructure, and secretion. J Torrey Bot Soc. 135(2):155-167.doi:10.3159/07-RA-045.1.
Kambiré, D.A.; Yapi, T.A.; Boti, J.B.; Garcia, G.; Tomi, P.; Bighelli, A.; Tomi, F. Chemical composition of leaf essential oil of Piper umbellatum and aerial part essential oil of Piper guineense from Côte d’Ivoire. Nat. Prod. Commun. 2019, 14, 1–8.
Kameubun, K.M.B., Rehiara, R., Deminggus, F. (2020). Pemanfaatan Tumbuhan Diwoka (Piper macropiper Pennant.) oleh suku Dani, Wamena. Jurnal ilmu Pendidikan Indonesia. 8 (1), 37 – 45.
Liu, M, Liu, J. 2012. Structure and histochemistry of the glandular trichomes on the leaves of Isodon rubescens (Lamiaceae). Afr Biotechnol. 11(7): 4069-4078.
Nayaka,N.M.D.M.W.;Sasadara,M.M.V.;Sanjaya,D.A.;Yuda,P.E.S.K.;Dewi,N.L.K.A.A.;Cahyaningsih,E.;Hartati,R.Piperbetle (L): Recent review of antibacterial and antifungal properties, safety profiles, and commercial applications. Molecules 2021, 26, 2321.
Oliveira, A.B.D, Mendonça M.S.D, Azevedo, A.A, Meira R.M.S.A. 2012. Anatomy and histochemistry of the vegetative organs of Cissus verticillata- a native medicinal plant of the Brazilian Amazon. Rev Bras Farmacogn. 22(6): DOI: 10.1590/s0102-695x2012005000092.
Oliveira, G.L.; Moreira, D.D.; Mendes, A.D.; Guimarães, E.F.; Figueiredo, L.S.; Kaplan, M.A.; Martins, E.R. (2013) Growth study and essential oil analysis of Piper aduncum from two sites of Cerrado biome of Minas Gerais State, Brazil. Rev. Bras. Farmacogn. , 23, 743–753.
Rukmini, A., Utomo, D.H., Laily, A.N. (2020). Skrining fitokimia familia Piperaceae. Jurnal Biologi dan Pembelajarannya, 7 (1), Pp: 28-32 e-ISSN: 2406 - 8659
Saensouk, P., Boonma, T., et al. (2025). Ethnobotany of Piperaceae in Nakhon Nayok Province, Central Thailand, Biodiversita, 26 (5), 2416-2428. DOI: 10.13057/biodiv/d260539.
Salehi, B., Zakaria, Z.A., Gyawali, R., Ibrahim, S.A., et al. (2019). Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications. Molecules. 7;24(7):1364. DOI: 10.3390/molecules24071364
Sembiring, A.Y.S., Ariska, I.R.N. (2025). Studi Keanekaragaman dan Pemanfaatan Sirih sirihan (Piperaceae) Sebagai Obat Tradisioal di Desa Tanjung Merawa Kecamatan Tiganderket Kabupaten Karo. BioEksakta: Jurnal Ilmiah Biologi Unsoed, 7(2), 154-162. DOI. 10.20884/1.bioe.2025.7.2.15484
Septiani, F., Suriani, C., Panjaitan, G. et al. (2025). Studi etnobotani pemanfaatan sirih merah (Piper crocatum) dan kunyit (Curcuma longa) sebagai tanaman obat diabetes mellitus pada masyarakat suku Karo. Jurnal intelek dan cendikiawan nusantara. 2 (4).
Widuri, S.A., Sulistyaningsih, Y.C., Umar, A.H., Ratnadewi, D. (2024). Secretory structures and histochemistry of roots, stem, and leaves of medicinal plant Fibraurea tinctoria Lour. Microsc Res Tech. 87(12):3026-3036. DOI: 10.1002/jemt.24676. Epub 2024 Aug 9.
